Discover la Serenissima by gondola and ride with someone special under the Bridge of Sighs; wonder at the opulence of Ducal palaces and try on a gaudy, feather-bedecked Carnival mask. Linger over cappuccino on the Ca d’Oro, and be sure to dodge the pigeons in the Piazza before you step into San Marco Cathedral for an eyeful of giltwork and divine frescoes.

In Croatia, the Old Town of Split wraps around the luxurious palace where the Roman emperor Diocletian lived out his last days after abdicating in AD 305. Today, this remarkable white limestone palace, a UNESCO Site, awaits your discovery. Part luxurious villa, part military camp, the palace is enclosed by imposing walls and connected by roads linking the eastern Silver Gate with the Iron Gate to the west. Within: an octagonal domed mausoleum, temples and a monumental court accessing the imperial apartments.

While travelers have been visiting the Albanian Riviera since antiquity, the region is, with reason, often described as up-and-coming. Long overlooked because of Albania’s political isolation from the rest of Europe, this 80-kilometer (50-mile) stretch of the northern Ionian Sea has seaside towns and stunning blue waters that visitors are now rediscovering. Strange concrete pillboxes are still visible, but other vestiges of the Communist era are thankfully fading away. The southern anchor of this coast is Sarandë, whose ancient inhabitants were said to be the descendants of the ancient Greek hero Achilles. Today, the city has become a proverbial boomtown, with the population tripling in summer. Less than 10 miles from the popular Greek tourist island of Corfu, Sarandë now sees plenty of day-trippers coming over on the short ferry ride. With a smooth horseshoe curve to its waterfront, and with fine palm-lined promenades upon which young honeymooners stroll, one wonders: What took so long? Like a mini San Francisco, the city is built around a series of stairs that lead from the top of the hill, dominated by a castle, down to the seafront. Its easy access to the sea helps explain the city’s reputation for serving excellent, fresh seafood. Sarandë is also a convenient base from which to visit a plethora of ancient ruins and UNESCO World Heritage Sites.

In the quiet of the original Olympic stadium, where the torch was first lit and the winners were crowned with a laurel wreath, let your imagination run. Step into the ruined archives of Greek mythology at the Temple of Zeus—one of the few remaining Wonders of the Ancient World.

The port of Souda on the Aegean Sea is home to a Greek and NATO naval base and is located six kilometers (three miles) from Chania—the second-largest city on Crete, which itself is the largest of the Greek Islands. Once you’re in Chania, set your compass for the historic waterfront with its famous Venetian Harbor dating to the 14th century. Walk along the breakwater to the restored 500-year-old lighthouse for views that are particularly photogenic from late afternoon until sunset. The atmospheric tangle of streets that is Old Town is easily explored on foot, and you can stop at one of the many outdoor cafés for a bouyatsa (custard pastry) or a glass of Cretan red wine.Soúda can also be a jumping-off point for a visit to Rethymnon, located about 54 kilometers (33 miles) to the east. Shaped by centuries of invasion, namely by the Venetians and Turks, its Fortezza was built by the Venetians in the late 16th century and captured by the Ottomans in 1646. The Old Town has the same kind of architectural character as Chania, but on a smaller scale.

Informality rules on this sunny isle where pleasure-seekers from around the world come to play. Ramble along narrow streets past white-washed houses and blue-domed churches, bouganvillea-covered walls and thread-like, step-laden footpaths leading everywhere.

Thick sandstone walls fortify Valletta, holding within its stone streets and glorious architecture. It fees like a travesty, walking over the detailed inlaid marble floors of the the cathedrals, but they are there to be seen and appreciated. The Silent City is Mdina, on the far side of the island, where no cars are permitted to disrupt the serene streets. Keep an eye out for the legendary, aged yellow buses of Malta which appear to be on their last legs, but are in fact a revered and flawlessly maintained piece of Maltese heritage.

Thick sandstone walls fortify Valletta, holding within its stone streets and glorious architecture. It fees like a travesty, walking over the detailed inlaid marble floors of the the cathedrals, but they are there to be seen and appreciated. The Silent City is Mdina, on the far side of the island, where no cars are permitted to disrupt the serene streets. Keep an eye out for the legendary, aged yellow buses of Malta which appear to be on their last legs, but are in fact a revered and flawlessly maintained piece of Maltese heritage.

Victoria is aptly known by the local Maltese as Rabat, an Arabic word meaning “suburb outside the fortress walls.” The fortress in this case is the massive, hill top Citadel first fortified during the Bronze Age around 1500 BC. Walk the fortress walls for a 360° view of Gozo; visit the exquisite 17th century baroque Cathedral; stroll the gardens of Villa Rundle; and shop for fine weaving, lace and silver filigree. Sample shore excursions: Victoria’s Secrets; Gozo Arts & Crafts; A Taste of Gozo.

Territory of the legendary Godfather, Sicily has hosted many film crews, and Palermo in particular is home to the Opera House where Al Pacino’s character met his Waterloo in the Godfather III. Also in Palermo are a Spanish church with a Moorish cloister and a cathedral whose electic facade speaks volumes about all those who came, saw and conquered. Enjoy it all as you would the caponata—sweet and tangy and, not surprisingly, delicious.

Rising behind the wide curve of its bay with brooding Mount Vesuvius and the deep blue sea as a backdrop, Naples, Italy enjoys a magnificent natural setting. It is the third-largest city in Italy after Rome and Milan, and arguably the most colorful and seductive of them all: Splendor and squalor live side by side in 21st-century Naples, and the mix is intoxicating. Cruise to Naples, home to world-class museums and attractions. Naples has something for everyone – superb restaurants, eclectic shopping, a thriving contemporary art scene and an edgy and vibrant street life. But once you’ve had enough of the pounding traffic and jostling crowds while sightseeing in Naples, there are endless opportunities for exploration further afield. The celebrated Roman ruins of Pompeii and Herculaneum, both victims of Vesuvius’ devastating 79 C.E. eruption, lie just south of the city. Explore Naples’ history or take a short ride over to the island of Capri on a Naples shore excursion. The delightful town of Sorrento and the magnificent scenery of the Amalfi Coast are also within easy reach, and the dolce vita glamour of Capri—not to mention the healing thermal waters of Ischia—are a short hydrofoil hop from the mainland. Naples cruises offer a perfect mix of cultural and natural attractions.

When you embark on a cruise to Rome with Holland America Line you experience its bustling modernism along with its rich history. You can walk in the footsteps of emperors, have coffee in Renaissance piazzas and see contemporary art all in one afternoon. Your sightseeing time in Rome begins at the nearby port of Civitavecchia, a seaside town with roots that stretch back to the Etruscan era. Take note of the Forte Michelangelo (both Bramante and Michelangelo had a hand in its design), and the lungomare, a lively stretch along the sea with beach clubs, bars and restaurants. Once in the Eternal City you can fill your day with museums, churches, archaeological sites, traditional trattorias, artisan shops and, of course, gelato. The Colosseum and the Vatican Museums are Rome’s superstar attractions, but there are plenty of quieter gems to explore. For food lovers there are the markets in Campo de’ Fiori or the slightly farther flung Testaccio. The hip neighborhood of Monti, next to the Colosseum, has a vibrant piazza scene and boutique shopping, while the Villa Borghese offers a green oasis with a view towards Saint Peter’s Basilica and the masterpiece-filled Galleria Borghese. Although Rome might not have been built in one day, you’ll certainly be able to see its highlights on our Rome cruises along with the top things to do there in 24 hours.